Cognitive
Allopregnanolone
Natural neurosteroid that enhances GABA-A receptor signalling.
- Third-party tested
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Overview
Allopregnanolone is made in the body from progesterone. It strengthens the calming effect of GABA at GABA-A receptors, the main inhibitory receptors in the brain.
Its levels change sharply around pregnancy and childbirth, and a formulation of it (brexanolone) is an approved treatment for postpartum depression.
Research areas
- GABA-A receptor modulation
- Mood and postpartum depression
- Stress and anxiety
Specifications
- Category
- Cognitive
- Compound
- Neurosteroid (progesterone metabolite)
- Structure
- Not a peptide
- Form
- Powder
- Available as
- 500mg (Ultra-Pure Powder)
- Quality
- Third-party tested
Storage and handling
Store sealed in a cool, dry place, away from light and moisture. Freezer storage (−20 °C) extends shelf life.
Sold strictly for laboratory research use only. Not for human consumption, and not intended to diagnose, treat, cure or prevent any disease.