Cagrilintide

Overview

Amylin is a hormone released together with insulin after meals. It slows stomach emptying and acts on the brain to signal satiety. Native amylin is short-lived and tends to clump, so cagrilintide was designed as a stable, long-acting version with a fatty acid chain that binds albumin.

It activates both amylin and calcitonin receptors and is studied on its own and, more often, together with GLP-1 agonists such as semaglutide.

Research areas

• Satiety signalling and food intake
• Body-weight regulation
• Amylin and GLP-1 combination pharmacology

Specifications

Category

Weight loss

Compound

Synthetic, acylated amylin analogue

Structure

Amylin-based peptide with a fatty acid side chain

Form

Lyophilised (freeze-dried) powder in sealed vials

Available as

5mg (10 vials) · 10mg (10 vials)

Quality

Third-party tested

Storage and handling

Unopened vials: freezer (−20 °C) for long-term storage, or refrigerator (2–8 °C) for shorter periods. Keep away from light and moisture. After reconstitution, keep refrigerated.